GLP-1 Elite

Rx Only

Semaglutide + Tirzepatide

Stalled on a single GLP-1? This combines semaglutide and tirzepatide to work across three receptor targets at once. It’s a stronger, broader approach built to push past stubborn plateaus, with dosing and side effects monitored closely.

Same Pricing - All Doses

Delivery of Medication Every 4 Weeks

Ongoing Provider Care & Support

Free Shipping

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Select Package:

WHATS INCLUDED

Video visit every 90 days

Metabolic lab testing every 6 months

Injection Supplies (Syringes, Needles & Alcohol Swabs)

Free Shipping

What is

GLP-1 Elite

This compound combines semaglutide and tirzepatide, engaging your body's GLP-1 receptors from two complementary angles while also activating GIP receptors through tirzepatide's dual action. This broader receptor coverage means appetite signaling, digestion, and insulin and glucagon regulation are all addressed more fully than with a single-agent approach, which is why it's often recommended for those who've plateaued on standard GLP-1 treatment or want steadier, more balanced support across appetite and blood sugar.

Your compound is prepared at a licensed 503A pharmacy, meaning it's made specifically for you under a valid prescription, and every batch is third-party tested for purity and potency before it reaches your door.

GLP-1 Elite

Benefits

How the Combination Works

Semaglutide acts on the GLP-1 pathway, while tirzepatide acts on both GIP and GLP-1 pathways. Your prescribed plan determines how these medications are used as part of your overall weight-loss care.

More Complete Appetite Support

Semaglutide and tirzepatide work across GLP-1 and GIP pathways to help reduce hunger, quiet food noise, and make it easier to feel satisfied with less.

Stronger Metabolic Support

Together, semaglutide and tirzepatide support weight loss while helping regulate appetite, blood sugar, and insulin response.

Less Strain on the Body

As excess weight comes down, there may be less pressure on your joints and greater comfort in everyday movement.

Support for Heart Health

Improvements in weight and metabolic health may also benefit blood pressure, cholesterol, and other markers tied to cardiovascular health.

More Consistent Energy

Better blood sugar regulation and improved metabolic health may help support steadier energy and clearer focus throughout the day.

Your Ongoing Care

Your treatment is provider-guided from day one and adjusted as you go. You'll have a video visit every 90 days and metabolic lab testing every 6 months, so your provider can track your progress and fine-tune your dose based on your results and how you're feeling. Between visits, you have ongoing access to your care team for questions, side effect support, or dose changes, all with the same provider and the same standard of care at every step.

Shipping & Delivery

Your medication ships directly to your door every 4 weeks, with free shipping on every delivery. Because your compound needs to stay cold, it arrives in insulated, temperature-controlled packaging with ice packs to protect it in transit. Once it arrives, store it in the refrigerator as instructed by your provider. Each shipment comes ready to use, with your dose already set, so there's nothing extra to coordinate.

TRANSPARENT PRICING

Most healthcare pricing is a mystery. We think you deserve better than that.

What Members Pay:

$99 a month

You Saved:

$100 a month

Learn More About Our Transparent Pricing

Manufacturing

$1.73

15% Markup

$0.26

Pharmacy Labor

$5.00$5.25

Standard Shipping

$5.25

REAL STORIES REAL PROGRESS

See the remarkable journeys of our clients who achieved lasting weight loss and renewed confidence through personalized GLP-1 therapy.

Jennifer Cox

WEIGHT LOSS

-47 lbs

TIMEFRAME

6 months

Before

After

Michelle Eury

WEIGHT LOSS

-39 lbs

TIMEFRAME

4.5 months

Before

After

Kelli Huff

WEIGHT LOSS

-35 lbs

TIMEFRAME

4 months

Before

After

Lesly Martinez

WEIGHT LOSS

-51 lbs

TIMEFRAME

8 months

Before

After

Rebecca Southerland

WEIGHT LOSS

-48 lbs

TIMEFRAME

6 months

Before

After

PAY LESS. SAVE MORE.

PAY LESS FOR YOUR WEIGHT LOSS TREATMENT

Members pay provider pricing on their GLP-1 and every other medication in our catalog. Straightforward, transparent pricing and an average savings of XX% on medications alone.

Most members cover the cost of their membership through medication savings alone. Everything else is just upside.

EverPrime

Aids in regulating glucose levels

Increases your daily energy levels

Slows digestion

Reduces appetite and control cravings

Aids in regulating glucose levels

Increase your daily energy levels

Slows digestion

Reduces appetite and control cravings

STAY ON TRACK

We track your progress over time on our platform every step of the way.

Unlike typical programs that only provide a lab report, your coach analyzes your results, integrates insights, and creates a data-driven plan aimed at achieving results. See your progress clearly, all in one place.

Start Intake

4 SIMPLE STEPS

TELL US ABOUT YOU

Share your health history, goals and what you have already tried.

Woman in blue scrubs writing on clipboard while using a laptop at a white desk.

MEET YOUR PROVIDER

A licensed provider reviews your information and helps determine the right path forward.

Closed cardboard box with the text ENHANCE.MD on the lid, placed on a textured surface with shadows.

START YOUR PLAN

If approved, your treatment is prescribed and delivered directly to your door.

Smiling older man holding a glass of drink and using a laptop at a table.

KEEP MOVING FORWARD

Your provider follows your progress and adjusts your care as your needs change.

TELL US ABOUT YOU

Share your health history, goals and what you have already tried.

MEET YOUR PROVIDER

A licensed provider reviews your information and helps determine the right path forward.

START YOUR PLAN

If approved, your treatment is prescribed and delivered directly to your door.

KEEP MOVING FORWARD

Your provider follows your progress and adjusts your care as your needs change.

METABOLIC WELLNESS

Rx ONLY

GLP-1 Advanced

Tirzepatide

WEIGHT LOSS

$99

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

GLP-1 Elite

Semaglutide + Tirzepatide

WEIGHT LOSS

$189

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

GLP-1 Semaglutide

Semaglutide

WEIGHT LOSS

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Microdosing Tirzepatide

Injection

LONGEVITY

$169

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

BPC-157

Injections

PEPTIDES

$99

member pricing

$189

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Methylene Blue

Oral capsule

LONGEVITY

$99

member pricing

$189

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Scream Cream

Topical cream

WOMEN'S SEXUAL HEALTH

$99

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

PT-141 Injectable

Injection

WOMEN'S SEXUAL HEALTH

$189

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

PT-141 Nasal Spray

Intranasal spray

WOMEN'S SEXUAL HEALTH

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Glutathione

Injection

LONGEVITY

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Metformin

Oral tablet

LONGEVITY

$99

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Trazodone

Oral tablet

LONGEVITY

$189

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

LDN

Oral Capsule

LONGEVITY

$29

member pricing

$99

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Vitamin B12

Injection

LONGEVITY

$49

member pricing

$189

standard pricing

COMPARE MEDICATIONS

Rx ONLY

NAD+ Injection

Injection

LONGEVITY

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

NAD+ Wafer

Oral wafer

LONGEVITY

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

NAD+ Nasal Spray

Intranasal spray

LONGEVITY

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Sermorelin

Injection

LONGEVITY

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Rosuvastatin

Oral tablet

LONGEVITY

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Ezetimibe

Oral tablet

LONGEVITY

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

Rx ONLY

Oxytocin Nasal Spray

Intranasal spray

WOMEN'S SEXUAL HEALTH

$49

member pricing

$280

standard pricing

COMPARE MEDICATIONS

HOW MUCH CAN YOU LOSE

20%

In a 72-week clinical study, adults taking tirzepatide lost an average of approximately 20% of their starting body weight.

Adults taking semaglutide lost an average of approximately 14% in the same head-to-head study.

Source: SURMOUNT-5 clinical trial, New England Journal of Medicine, 2025. Results reflect branded medications taken at maximum tolerated doses for 72 weeks. Our compounded medications use the same active ingredients but have not been studied in separate clinical trials, so results may differ. Individual results vary.

Select your current height

FEET

INCHES

Select your current weight 144 lbs

Weight you could lose 21lbs

Based on average results from a 72-week clinical study using maximum tolerated doses alongside diet and exercise. Individual results vary.

Start Intake

START YOUR WEIGHT-LOSS FOR THE LAST TIME

Up to 15% weight loss *

Join EverPrime

EXPERT LED TEAM

Professionals you can count on every step of the way

Dr. ERIK STARK

Medical Director

Dr. Erik Stark is a board-certified orthopedic and sports medicine surgeon with expertise in obesity and longevity medicine. A lifelong athlete and jiu-jitsu black belt, he combines clinical expertise with a performance-focused approach to helping patients stay strong, active, and healthy.

ELISA GEORGE

CEO

Elisa George is CEO of Everprime and a brand, growth, and business executive with 18 years of experience building and scaling consumer businesses. She brings deep expertise in brand strategy, product development, growth, and consumer experience, with a particular passion for women’s health, wellness, and longevity.

Dr. VISHAL VERMA

Clinical Advisor

Dr. Vishal Verma is Executive Chairman of EverPrime and a physician, healthcare executive, and serial entrepreneur. With decades of experience building and leading healthcare companies, he brings deep expertise in healthcare innovation, technology, longevity, and wellness.

MEDICAL DIRECTOR

Dr. ERIK STARK

Medical Director

OPERATIONAL DIRECTOR

ELISA GEORGE

CEO

CLINICAL ADVISOR

Dr. VISHAL VERMA

Clinical Advisor

HAVE QUESTIONS?

What is a semaglutide/tirzepatide combo treatment plan?

This plan incorporates semaglutide and tirzepatide, two medications that act on hormone pathways involved in hunger, fullness, digestion, blood sugar and insulin response. Semaglutide activates the GLP-1 receptor, while tirzepatide activates both GIP and GLP-1 receptors.

How does semaglutide and tirzepatide support weight loss?

Semaglutide and tirzepatide can help reduce hunger, increase feelings of fullness and support more consistent eating patterns. Because the medications work across GLP-1 and GIP pathways, the prescribed plan is designed to support appetite and metabolic health as part of a broader weight loss program.

Who may be eligible for this plan?

Eligibility depends on your weight, health history, current medications, pregnancy plans and overall treatment goals. A licensed provider reviews your information before prescribing and determines whether this plan fits your individual needs.

How much weight can you lose with semaglutide/tirzepatide combo?

Results vary, and there is not an established average specifically for using semaglutide and tirzepatide as one treatment plan. Your progress may depend on your prescribed doses, starting weight, consistency, lifestyle and individual response.

How long does it take to work?

Some people may notice changes in hunger, cravings or fullness within the first few weeks, while weight loss usually develops more gradually. Timing can vary based on the prescribed plan, dose changes and how your body responds.

How often is the semaglutide/tirzepatide combo taken?

Your dosing schedule is determined by your provider based on your treatment plan, response, and tolerance. GLP-1s are commonly prescribed as weekly injections, but the exact dose and timing may vary. Always follow the instructions provided with your prescription.

What are the possible side effects?

Both semaglutide and tirzepatide can cause gastrointestinal side effects such as nausea, diarrhea, vomiting, constipation and abdominal discomfort. Side effects may be more noticeable when treatment begins or doses change. Contact your provider if symptoms are severe, persistent or concerning.

Does Semaglutide/Tirzepatide Combo cause muscle loss?

Any type of weight loss can include some loss of lean muscle, whether it happens through medication, diet, exercise, or a combination of approaches. Semaglutide/Tirzepatide Combo does not uniquely cause muscle loss, but it is still important to protect muscle as you lose weight. Eating enough protein and including regular strength training can help preserve lean mass, support strength, and improve the quality of your weight loss.

Who should not use semaglutide or tirzepatide?

These medications should not be used by people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Treatment may also be unsuitable during pregnancy or for people with certain medical conditions, allergies or medication interactions. Your provider will review your complete medical history before prescribing treatment.

How much does the semaglutide and tirzepatide plan cost?

Pricing depends on the program length and whether you choose a membership. Enhance.MD displays medication, membership and renewal pricing upfront so you can understand and compare the full cost before getting started.

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