Methylene Blue

Rx Only

Oral capsule

When mental energy feels low and focus is harder to maintain, methylene blue supports cellular energy pathways tied to brain function, clarity, and cognitive performance.

Provider Care Throughout Treatment

Convenient Home Delivery

Care Built Around Your Goals

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WHATS INCLUDED

Licensed provider evaluation
Ongoing treatment review and provider support
One-time G6PD lab testing
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What is

Methylene Blue

Methylene blue is a medication with a long history of medical use that also plays a role in cellular redox activity, the process cells use to transfer and manage energy. In longevity care, it is often used to support mitochondrial function, mental energy, and cognitive performance. By helping cells use oxygen and produce energy more efficiently, methylene blue offers a cellular approach to focus, clarity, and brain health.

Your treatment is part of a broader care plan, with licensed provider oversight, ongoing support, and guidance as your needs and goals change over time.

Your compound is prepared at a licensed 503A pharmacy, meaning it's made specifically for you under a valid prescription, and every batch is third-party tested for purity and potency before it reaches your door.

Methylene Blue

Benefits

How Methylene Blue Works

Methylene blue interacts with cellular redox pathways involved in how mitochondria use oxygen and produce energy. In longevity care, it is used to support cellular energy and the high energy demands of the brain.

Support for Mental Clarity

More efficient cellular energy production may help support clearer thinking and greater mental sharpness.

More Consistent Mental Energy

Methylene blue is designed to support the energy brain cells need to stay engaged throughout the day.

Support for Cognitive Performance

By supporting mitochondrial activity, it may help promote attention, memory, and overall cognitive function.

Cellular Resilience

Healthy mitochondrial function helps cells respond to the everyday demands of stress, activity, and aging.

Your Ongoing Care

Your treatment is provider-guided from the start, with ongoing reviews to make sure methylene blue continues to be appropriate for you. A one-time G6PD lab test is completed as part of treatment, and your provider will continue to review your medications and how you’re responding over time. Your care team is available for questions, side effect support, or changes in your health or medication list.

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$99 a month

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Manufacturing

$1.73

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$0.26

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$5.00

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EverPrime

Boost focus and brain health

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EXPERT LED TEAM

Professionals you can count on every step of the way

Dr. ERIK STARK

Medical Director

Dr. Erik Stark is a board-certified orthopedic and sports medicine surgeon with expertise in obesity and longevity medicine. A lifelong athlete and jiu-jitsu black belt, he combines clinical expertise with a performance-focused approach to helping patients stay strong, active, and healthy.

ELISA GEORGE

CEO

Elisa George is CEO of Everprime and a brand, growth, and business executive with 18 years of experience building and scaling consumer businesses. She brings deep expertise in brand strategy, product development, growth, and consumer experience, with a particular passion for women’s health, wellness, and longevity.

Dr. VISHAL VERMA

Clinical Advisor

Dr. Vishal Verma is Executive Chairman of EverPrime and a physician, healthcare executive, and serial entrepreneur. With decades of experience building and leading healthcare companies, he brings deep expertise in healthcare innovation, technology, longevity, and wellness.

MEDICAL DIRECTOR

Dr. ERIK STARK

Medical Director

OPERATIONAL DIRECTOR

ELISA GEORGE

CEO

CLINICAL ADVISOR

Dr. VISHAL VERMA

Clinical Advisor

HAVE QUESTIONS?

What is Methylene Blue, and what is it used for?

Methylene Blue works at the cellular level to support how your body produces energy and helps protect cells from oxidative stress. Researchers are studying whether these effects may support mental clarity, focus, and energy. The research in people is still early, especially for cognitive benefits, so we do not promise improvements in memory or thinking. Your provider will explain what Methylene Blue may help with, monitor how you respond, and adjust your treatment when needed. Because dosing is important, Methylene Blue is prescribed carefully and managed by your provider with safety in mind.

What’s the difference between the Methylene Blue prescribed by EverPrime and products sold over the counter?

The Methylene Blue prescribed through EverPrime is prepared by licensed compounding pharmacies and intended for medical use. These pharmacies follow established quality standards for purity, consistency, and accurate dosing. Over-the-counter products may be manufactured for laboratory, industrial, or other non-medical uses and may not meet the same standards for purity or dosing. For that reason, we recommend using only Methylene Blue that has been prescribed for you and dispensed through an appropriate pharmacy.

Can I receive Methylene Blue therapy if I take prescription medications?

Methylene Blue can interact with certain medications, especially antidepressants such as SSRIs and SNRIs, because it has MAOI activity. In some cases, these interactions can be serious, including the risk of serotonin syndrome. Before starting treatment, our clinical team carefully reviews your current medications and health history, and we may coordinate with your prescribing provider if changes are needed. We also screen for G6PD deficiency, since Methylene Blue may not be safe for people with this condition. Because these risks can be reduced but not completely eliminated, Methylene Blue therapy is carefully provider-managed and individualized for each patient.

How do you approach Methylene Blue therapy in patients on multiple medications, particularly antidepressants or other psychoactive agents?

We conduct a thorough drug interaction analysis prior to initiation, with a focus on avoiding serotonergic overload or hypertensive crises linked to MAOI activity. Where appropriate, medication adjustments are coordinated with your prescribing physicians to maintain therapeutic synergy and safety.

When should I take Methylene Blue, and how often?

Methylene Blue is typically taken earlier in the day, as it may support alertness and mental clarity. Taking it too late in the afternoon or evening may interfere with sleep for some people. How often you take Methylene Blue will depend on your individual treatment plan, including your dose, how you respond to therapy, and your overall health. Your provider will recommend a schedule that is appropriate for you and may adjust the timing or frequency based on your response.

When can I expect to notice subtle shifts in cognitive clarity or energy after starting Methylene Blue therapy?

Patients often report enhanced mental acuity and mitochondrial energy optimization within 1 to 2 hours post-dose, due to Methylene Blue’s facilitation of electron transport in mitochondria. Cumulative cognitive and mood benefits typically consolidate over 1 to 2 weeks of consistent use, reflecting neuroprotective and metabolic adaptations.

How is my Methylene Blue dose determined?

Your Methylene Blue treatment plan is personalized based on your overall health, current medications, and individual needs. Before treatment, our clinical team reviews your medication regimen carefully, especially antidepressants such as SSRIs and SNRIs, because Methylene Blue can cause serious interactions with certain medications. Your provider will determine whether Methylene Blue is appropriate for you and, if so, select a dose designed to balance safety and potential benefit. Your response to treatment may also be monitored over time so your plan can be adjusted as needed.

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