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GLP-1 Semaglutide

Semaglutide
$49
member pricing
$280
standard pricing
When hunger and cravings feel constant, weight loss feels harder than it should. Semaglutide helps you feel fuller sooner, think about food less, and make steady progress as food noise begins to quiet.
Same Pricing - All Doses
Delivery of Medication Every 4 Weeks
Ongoing Provider Care & Support
Free Shipping
/MO
$249
/mo
$237
/mo
$224
/mo
$214
/mo
Best Value
/MO
$150
/mo
$138
/mo
$125
/mo
$115
/mo
GLP-1 Semaglutide
$129 /mo
Est. total this month
Membership is billed on its own schedule and covers more than this medication — see below.
$228 /mo
Continue with Treatment
Thank you! Your submission has been received!
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/MO
$249
/mo
$237
/mo
$224
/mo
$214
/mo
Best Value
/MO
$150
/mo
$138
/mo
$125
/mo
$115
/mo
GLP-1 Semaglutide
$129 /mo
EverPrime Membership
$99 /mo
Est. total this month
Membership is billed on its own schedule and covers more than this medication — see below.
$228 /mo
Continue with Membership
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Select Package:
WHATS INCLUDED

Initial video visit with a licensed provider
Ongoing treatment review and provider support
Metabolic lab testing every 6 months
Syringes, needles, and alcohol swabs included
Free shipping

What is
GLP-1 Semaglutide
?

Semaglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1 (GLP-1), a hormone your gut releases after eating to help regulate appetite, digestion, and blood sugar. By activating GLP-1 receptors, it quiets appetite signals in the brain, slows digestion so fullness lasts longer, and helps the pancreas balance insulin and glucagon, which together lead to steadier blood sugar and gradual, sustainable weight loss.

Your compound is prepared at a licensed 503A pharmacy, meaning it's made specifically for you under a valid prescription, and every batch is third-party tested for purity and potency before it reaches your door.

GLP-1 Semaglutide
Benefits
How Semaglutide Works

Semaglutide mimics GLP-1, a naturally occurring hormone involved in appetite and blood sugar regulation. It helps you feel fuller longer, reduces hunger, and supports more consistent eating patterns.

Better Appetite Control

Semaglutide works with GLP-1 receptors involved in hunger and fullness, helping reduce appetite and making it easier to feel satisfied with less food.

More Balanced Metabolic Health

It supports weight loss while helping the body regulate blood sugar through glucose-dependent effects on insulin and glucagon.

Less Strain on the Body

Losing excess weight may reduce pressure on the joints, make movement easier, and improve comfort in everyday life.

Support for Heart Health

Improvements in weight and metabolic health may benefit blood pressure, cholesterol, and other markers tied to cardiovascular health.  

Healthier Years Ahead

Reaching and maintaining a healthier weight may help reduce the risk of health conditions associated with obesity.

Your Ongoing Care
Your treatment is provider-guided from day one and adjusted as you go. You’ll start with a video visit, followed by ongoing treatment reviews and provider support as you continue care. Metabolic lab testing is completed every 6 months so your provider can track your progress and make changes when appropriate. Between reviews, you’ll have access to your care team for questions, side effect support, or treatment updates, with consistent oversight throughout your plan.
Shipping & Delivery
Your medication ships directly to your door every 4 weeks, with free shipping on every delivery. Because your compound needs to stay cold, it arrives in insulated, temperature-controlled packaging with ice packs to protect it in transit. Once it arrives, store it in the refrigerator as instructed by your provider. Each shipment comes ready to use, with your dose already set, so there's nothing extra to coordinate.

TRANSPARENT PRICING

Most healthcare pricing is a mystery. We think you deserve better than that.
What Members Pay:
$99 a month
You Saved:
$100 a month
Learn More About Our Transparent Pricing
Manufacturing
$1.73
15% Markup
$0.26
Pharmacy Labor
$5.00
Standard Shipping
$5.25

REAL STORIES REAL PROGRESS

See the remarkable journeys of our clients who achieved lasting weight loss and renewed confidence through personalized GLP-1 therapy.
Jennifer Cox
WEIGHT LOSS
-47 lbs
TIMEFRAME
6 months
Before
After
Michelle Eury
WEIGHT LOSS
-39 lbs
TIMEFRAME
4.5 months
Before
After
Kelli Huff
WEIGHT LOSS
-35 lbs
TIMEFRAME
4 months
Before
After
Lesly Martinez
WEIGHT LOSS
-51 lbs
TIMEFRAME
8 months
Before
After
Rebecca Southerland
WEIGHT LOSS
-48 lbs
TIMEFRAME
6 months
Before
After
PAY LESS. SAVE MORE.

PAY LESS FOR YOUR WEIGHT LOSS TREATMENT

Members pay provider pricing on their GLP-1 and every other medication in our catalog. Straightforward, transparent pricing and an average savings of XX% on medications alone.

Most members cover the cost of their membership through medication savings alone. Everything else is just upside.
EverPrime
Aids in regulating glucose levels
Increases your daily energy levels
Slows digestion
Reduces appetite and control cravings
Aids in regulating glucose levels
Increase your daily energy levels
Slows digestion
Reduces appetite and control cravings

STAY ON TRACK

We track your progress over time on our platform every step of the way.

Unlike typical programs that only provide a lab report, your coach analyzes your results, integrates insights, and creates a data-driven plan aimed at achieving results. See your progress clearly, all in one place.

4 SIMPLE STEPS

01
TELL US ABOUT YOU
Share your health history, goals and what you have already tried.
Woman in blue scrubs writing on clipboard while using a laptop at a white desk.
02
MEET YOUR PROVIDER
A licensed provider reviews your information and helps determine the right path forward.
Closed cardboard box with the text ENHANCE.MD on the lid, placed on a textured surface with shadows.
03
START YOUR PLAN
If approved, your treatment is prescribed and delivered directly to your door.
Smiling older man holding a glass of drink and using a laptop at a table.
04
KEEP MOVING FORWARD
Your provider follows your progress and adjusts your care as your needs change.
01
TELL US ABOUT YOU
Share your health history, goals and what you have already tried.
Woman in blue scrubs writing on clipboard while using a laptop at a white desk.
02
MEET YOUR PROVIDER
A licensed provider reviews your information and helps determine the right path forward.
Closed cardboard box with the text ENHANCE.MD on the lid, placed on a textured surface with shadows.
03
START YOUR PLAN
If approved, your treatment is prescribed and delivered directly to your door.
Smiling older man holding a glass of drink and using a laptop at a table.
04
KEEP MOVING FORWARD
Your provider follows your progress and adjusts your care as your needs change.

METABOLIC WELLNESS

Steady Foundational Weight Loss
GLP-1 (Semaglutide)
IDEAL FOR
First time users or moderate goals
WHAT TO EXPECT
Gradual consistent progress
INCLUDED CARE
Provider care + lifestyle coaching + labs
Stronger Apetite Control, Faster Momentum
GLP-1 + GIP Tirzepatide
IDEAL FOR
Stronger appetite suppression and glucose control
WHAT TO EXPECT
Faster progress than Core, steadier  momentum
INCLUDED CARE
Provider care + lifestyle coaching + labs
Maximum Support Challenging Plateaus
Dual GLP-1 + GIP (Semaglitide + Tirzepatide)
IDEAL FOR
Plateaued patients currently on Semaglutide or Tirzepatide
WHAT TO EXPECT
Enhanced support when porogress has slowed
INCLUDED CARE
Provider care + lifestyle coaching
Long Term Metabolic Support, Greater Comfort
GLP-1 + GIP Tirzepatide — Low dose
IDEAL FOR
Individuals seeking metabolic support with greater comfort and control
WHAT TO EXPECT
Subtle sustained support with improved tolerabitlity
INCLUDED CARE
Provider care + lifestyle coaching + labs
Rx ONLY

GLP-1 Advanced

Tirzepatide
WEIGHT LOSS
$99
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

GLP-1 Elite

Semaglutide + Tirzepatide
WEIGHT LOSS
$189
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

GLP-1 Semaglutide

Semaglutide
WEIGHT LOSS
$49
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

Microdosing Tirzepatide

Injection
LONGEVITY
$169
member pricing
$280
standard pricing
See More
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Rx ONLY

BPC-157

Injections
PEPTIDES
$99
member pricing
$189
standard pricing
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Rx ONLY

Methylene Blue

Oral capsule
LONGEVITY
$99
member pricing
$189
standard pricing
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Rx ONLY

Scream Cream

Topical cream
WOMEN'S SEXUAL HEALTH
$99
member pricing
$280
standard pricing
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Rx ONLY

PT-141 Injectable

Injection
WOMEN'S SEXUAL HEALTH
$189
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

PT-141 Nasal Spray

Intranasal spray
WOMEN'S SEXUAL HEALTH
$49
member pricing
$280
standard pricing
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Rx ONLY

Glutathione

Injection
LONGEVITY
$49
member pricing
$280
standard pricing
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Rx ONLY

Metformin

Oral tablet
LONGEVITY
$99
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

Trazodone

Oral tablet
LONGEVITY
$189
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

LDN

Oral Capsule
LONGEVITY
$29
member pricing
$99
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

Vitamin B12

Injection
LONGEVITY
$49
member pricing
$189
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

NAD+ Injection

Injection
LONGEVITY
$49
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

NAD+ Wafer

Oral wafer
LONGEVITY
$49
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

NAD+ Nasal Spray

Intranasal spray
LONGEVITY
$49
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

Sermorelin

Injection
LONGEVITY
$49
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

Rosuvastatin

Oral tablet
LONGEVITY
$49
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

Ezetimibe

Oral tablet
LONGEVITY
$49
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS
Rx ONLY

Oxytocin Nasal Spray

Intranasal spray
WOMEN'S SEXUAL HEALTH
$49
member pricing
$280
standard pricing
See More
COMPARE MEDICATIONS

HOW MUCH CAN YOU LOSE

20%
In a 72-week clinical study, adults taking tirzepatide lost an average of approximately 20% of their starting body weight.

Adults taking semaglutide lost an average of approximately 14% in the same head-to-head study.
Source: SURMOUNT-5 clinical trial, New England Journal of Medicine, 2025. Results reflect branded medications taken at maximum tolerated doses for 72 weeks. Our compounded medications use the same active ingredients but have not been studied in separate clinical trials, so results may differ. Individual results vary.
Select your current height
FEET
5
INCHES
3
Select your current weight 144 lbs
Weight you could lose 21lbs

Based on average results from a 72-week clinical study using maximum tolerated doses alongside diet and exercise. Individual results vary.

START YOUR WEIGHT-LOSS FOR THE LAST TIME

Up to 15% weight loss *
Join EverPrime
Join EverPrime

EXPERT LED TEAM

Professionals you can count on every step of the way
Dr. ERIK STARK
Medical Director
Dr. Erik Stark is a board-certified orthopedic and sports medicine surgeon with expertise in obesity and longevity medicine. A lifelong athlete and jiu-jitsu black belt, he combines clinical expertise with a performance-focused approach to helping patients stay strong, active, and healthy.
ELISA GEORGE
CEO
Elisa George is CEO of Everprime and a brand, growth, and business executive with 18 years of experience building and scaling consumer businesses. She brings deep expertise in brand strategy, product development, growth, and consumer experience, with a particular passion for women’s health, wellness, and longevity.
Dr. VISHAL VERMA
Clinical Advisor
Dr. Vishal Verma is Executive Chairman of EverPrime and a physician, healthcare executive, and serial entrepreneur. With decades of experience building and leading healthcare companies, he brings deep expertise in healthcare innovation, technology, longevity, and wellness.
MEDICAL DIRECTOR
Dr. ERIK STARK
Medical Director
Dr. Erik Stark is a board-certified orthopedic and sports medicine surgeon with expertise in obesity and longevity medicine. A lifelong athlete and jiu-jitsu black belt, he combines clinical expertise with a performance-focused approach to helping patients stay strong, active, and healthy.
OPERATIONAL DIRECTOR
ELISA GEORGE
CEO
Elisa George is CEO of Everprime and a brand, growth, and business executive with 18 years of experience building and scaling consumer businesses. She brings deep expertise in brand strategy, product development, growth, and consumer experience, with a particular passion for women’s health, wellness, and longevity.
CLINICAL ADVISOR
Dr. VISHAL VERMA
Clinical Advisor
Dr. Vishal Verma is Executive Chairman of EverPrime and a physician, healthcare executive, and serial entrepreneur. With decades of experience building and leading healthcare companies, he brings deep expertise in healthcare innovation, technology, longevity, and wellness.

HAVE QUESTIONS?

What is semaglutide, and how does it work for weight loss?
Semaglutide is a GLP-1 receptor agonist that works by mimicking a hormone your body naturally produces to help regulate appetite, digestion, and blood sugar. It acts on areas of the brain involved in hunger and fullness, which can help reduce appetite and make it easier to feel satisfied with less food. It can also slow how quickly food leaves the stomach, helping fullness last longer. Over time, these effects can help reduce overall food intake and support meaningful weight loss as part of a broader plan that includes nutrition, physical activity, and ongoing care tailored to how your body responds.
Who is eligible for semaglutide treatment?
Semaglutide may be appropriate for adults with obesity, or adults who are overweight and have a weight-related condition such as high blood pressure, high cholesterol, prediabetes, or type 2 diabetes. Your provider will also look at factors like your weight history, what you’ve already tried, how your appetite and eating patterns have been affecting your progress, your current medications, and whether you have conditions that may make GLP-1 treatment less appropriate. Pregnancy plans, a history of certain gastrointestinal issues, and other medical risk factors also matter. Eligibility is based on the full picture, not BMI alone.
How much weight can you lose with semaglutide?
Weight loss with semaglutide typically happens gradually over several months, and results can vary quite a bit from person to person. Some people begin noticing changes in appetite and portion size early in treatment, while changes on the scale may take longer to build. How much weight you lose can depend on your starting weight, dose, how strongly your appetite responds, nutrition, activity, and how long you stay on treatment. In clinical studies, semaglutide has helped many patients achieve meaningful, sustained weight loss over time, but there is no single number that applies to everyone. Your provider will track your progress and adjust your treatment plan based on how your body is responding, with the goal of steady, sustainable progress rather than a specific target by a specific date.
How long does semaglutide take to work?
Some people notice changes in hunger, cravings, portion size, or how quickly they feel full within the first few weeks of treatment. Changes on the scale usually build more gradually over the following months. Semaglutide is typically started at a lower dose and increased over time, giving your body time to adjust while your provider looks at both effectiveness and side effects. Because of that, the first few weeks are often more about seeing how your body responds than judging your final results. Your provider will track your progress as your dose changes and adjust your treatment plan when appropriate.
What are the most common side effects of semaglutide?
The most common side effects are digestive and can include nausea, constipation, diarrhea, vomiting, reflux, and stomach discomfort. They are often most noticeable when you first start treatment or after your dose increases, and they may improve as your body adjusts. Your provider can help you manage side effects with changes to your dose, eating habits, hydration, or other supportive treatment when appropriate. Contact your provider if symptoms are severe, persistent, or making it difficult to eat or drink normally. Seek prompt medical care for severe abdominal pain that does not go away, especially with vomiting, and make sure your provider knows if you have a history of gallbladder or pancreatic problems.
Does semaglutide cause muscle loss?
Weight loss with semaglutide can include some loss of lean muscle, just as it can with weight loss from diet or other approaches. The goal is to lose more body fat while preserving as much muscle as possible. Eating enough protein and incorporating regular resistance or strength training can help support muscle preservation as you lose weight. Your provider can also track your progress and help make sure your treatment plan supports both weight loss and long-term strength.
Who should not take semaglutide?
Semaglutide should not be used by people with a personal or family history of medullary thyroid carcinoma or by people with Multiple Endocrine Neoplasia syndrome type 2. It is also not recommended during pregnancy. Before prescribing, your provider will review other factors that may affect whether semaglutide is appropriate for you, including a history of pancreatitis or gallbladder problems, significant gastrointestinal issues, current medications, and any previous reaction to semaglutide or another GLP-1 medication. Your medical history and current health status help determine whether treatment is a safe fit for you.
What is the difference between semaglutide and tirzepatide?
Semaglutide works on the GLP-1 receptor, while tirzepatide works on both GLP-1 and GIP receptors. Both hormones are involved in appetite, fullness, digestion, and blood sugar regulation, but tirzepatide targets two pathways instead of one. Enhance.MD also distinguishes semaglutide as GLP-1 and tirzepatide as GLP-1 + GIP in its weight-management materials. Both medications can help reduce hunger, increase fullness, and support weight loss, but people may respond differently to each. They can also differ in dosing, side effects, and the amount of weight loss seen across clinical studies. Choosing between them is not just about which medication is “stronger.” Your provider can look at your health history, labs, previous GLP-1 experience, side effects, and goals to decide which may be the better fit for you. Enhance.MD’s internal materials similarly position medication selection as something guided by labs and individual response rather than something patients need to figure out on their own.
What happens if I miss a dose of semaglutide?
What you should do depends on how much time has passed since your scheduled dose and the specific semaglutide product you are using. In some cases, you may be able to take the missed dose within a certain window. If too much time has passed, you may need to skip it and return to your regular schedule. Do not double your dose to make up for a missed one. Follow the instructions that come with your prescription or contact your provider if you are unsure what to do.
What happens when I reach my goal weight?
Reaching your goal weight does not automatically mean treatment stops. Your provider will look at how your weight, appetite, metabolic health, and lifestyle habits have changed and help you decide what maintenance should look like. That may involve continuing semaglutide, adjusting your dose, or developing a plan to transition off treatment while continuing habits that support your results. Appetite and weight can move back toward previous patterns after GLP-1 treatment is stopped, which is why having a longer-term maintenance plan matters. Enhance.MD’s internal materials similarly position the program around building habits and planning beyond the medication phase.

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