Trazodone

Rx Only

Oral tablet

When your body is tired but your mind will not fully settle, trazodone supports more consistent sleep so you can wake up feeling more rested and restored.

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What is

Trazodone

Trazodone is a prescription medication that affects serotonin signaling in the brain. Although originally developed as an antidepressant, it is also commonly prescribed in lower doses to support sleep. Its calming and sedating effects can help make it easier to fall asleep, stay asleep, and get more consistent rest.

Your treatment is part of a broader care plan, with licensed provider oversight, ongoing support, and guidance as your needs and goals change over time.

Trazodone

Benefits

How Trazodone Works

Trazodone affects serotonin signaling and has calming, sedating properties that can support sleep when taken at lower prescribed doses. Its pharmacology includes serotonin reuptake inhibition and 5-HT2 receptor antagonism.

Easier Sleep Onset

Its calming effects may help make the transition from wakefulness to sleep feel easier.

More Consistent Sleep

Trazodone may help reduce nighttime wakefulness and support longer periods of uninterrupted rest.

Better Overnight Recovery

More consistent sleep gives the brain and body greater opportunity to restore themselves overnight.

More Restored Mornings

Improved sleep continuity may help you wake feeling more rested and better prepared for the day.

Support for Long-Term Well-Being

Consistent, restorative sleep supports mood, cognition, physical recovery, and overall health.

Your Ongoing Care

Your treatment is provider-guided from the start, with ongoing reviews focused on how well it is supporting your sleep and how you’re feeling the next day. Your provider can help with questions about timing, effectiveness, side effects, or whether your treatment needs to change. Your care team remains available throughout treatment so you have support as your sleep needs evolve.

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Professionals you can count on every step of the way

Dr. ERIK STARK

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Dr. Erik Stark is a board-certified orthopedic and sports medicine surgeon with expertise in obesity and longevity medicine. A lifelong athlete and jiu-jitsu black belt, he combines clinical expertise with a performance-focused approach to helping patients stay strong, active, and healthy.

ELISA GEORGE

CEO

Elisa George is CEO of Everprime and a brand, growth, and business executive with 18 years of experience building and scaling consumer businesses. She brings deep expertise in brand strategy, product development, growth, and consumer experience, with a particular passion for women’s health, wellness, and longevity.

Dr. VISHAL VERMA

Clinical Advisor

Dr. Vishal Verma is Executive Chairman of EverPrime and a physician, healthcare executive, and serial entrepreneur. With decades of experience building and leading healthcare companies, he brings deep expertise in healthcare innovation, technology, longevity, and wellness.

MEDICAL DIRECTOR

Dr. ERIK STARK

Medical Director

OPERATIONAL DIRECTOR

ELISA GEORGE

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Clinical Advisor

HAVE QUESTIONS?

What is Trazodone, and why is it prescribed at EverPrime?

Trazodone is a prescription medication that is often used at lower doses to support sleep. At EverPrime, it may be prescribed for patients who have trouble falling asleep, staying asleep, or getting consistent, restful sleep. Unlike some traditional sleep medications, Trazodone is not a controlled substance and is generally considered to have a lower risk of dependence. Your provider will review your health history and other medications to determine whether it is a good fit for you.

Is Trazodone habit-forming or addictive?

Trazodone is not a controlled substance and is generally considered to have a low risk of addiction or misuse. However, your body can adjust to the medication over time, and stopping it suddenly may cause symptoms such as anxiety, agitation, or changes in sleep. If you decide to stop taking Trazodone, your provider may recommend gradually reducing your dose rather than stopping all at once.

How is Trazodone different from melatonin or other over-the-counter sleep aids?

Trazodone is a prescription medication that affects serotonin and has sedating effects that can help support sleep. Melatonin and many over-the-counter sleep aids work differently and may be appropriate for milder or occasional sleep concerns. Your provider may consider Trazodone when sleep problems are more persistent or when other options have not provided enough relief. They will review your symptoms, health history, and current medications to determine which approach is most appropriate for you.

What does Trazodone feel like? Will I feel groggy the next day?

Trazodone can make you feel sleepy or drowsy, which is why it is typically taken at bedtime. Some people find that it helps them settle into sleep more easily, while others may feel groggy, dizzy, or slower the next morning, especially when first starting treatment or after a dose change. Your response can vary based on your dose and how your body reacts to the medication. If morning grogginess is persistent or bothersome, your provider can help adjust your treatment plan.

How quickly does Trazodone start working?

Some people notice that Trazodone helps them fall asleep within the first few nights, while others may take longer to notice a consistent difference. Your response can continue to change over the first couple of weeks as your body adjusts to the medication. Your provider will monitor how you’re doing and can adjust your treatment plan if needed.

Can Trazodone help if anxiety is keeping me awake?

Trazodone affects serotonin and can have a calming, sedating effect that may make it easier to fall asleep when worry, racing thoughts, or tension are interfering with bedtime. It is not primarily prescribed as an anxiety treatment in this setting, and individual responses vary. Your provider will consider your sleep symptoms, mental health history, and other medications to determine whether Trazodone is an appropriate option for you.

What are the side effects of Trazodone?

Common side effects of Trazodone can include dizziness or lightheadedness, especially when standing up quickly, dry mouth, and next-morning drowsiness. These effects may be more noticeable when you first start treatment or after a dose change. A rare but serious side effect is priapism, a prolonged or painful erection that requires immediate medical attention. Before prescribing Trazodone, your EverPrime provider will review your health history and current medications to make sure it is a safe and appropriate option for you. If side effects are persistent or bothersome, your provider can adjust your treatment plan.

Can Trazodone interact with my medications or other treatments?

Yes. Trazodone can interact with certain medications, so your provider will review everything you are taking before prescribing it. Be sure to tell your provider if you take antidepressants such as SSRIs or SNRIs, or any other medication that affects serotonin. Some combinations can increase the risk of serotonin syndrome. This is especially important if Methylene Blue is part of your treatment plan, since combining it with serotonin-affecting medications can raise that risk and needs to be carefully screened first. Your provider will review your medications, supplements, and other treatments to determine whether Trazodone is appropriate for you and whether any changes or additional monitoring are needed.

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